The Russian Revolution Of 1917 - 1294 Words

Russia 1917, harsh working conditions, famine, and all power to one leader. Russia was living in discord presumably through political oppression, furthermore, political oppression inspires violence and terrorism. It affects daily residents because they’re under control of whoever is in charge. Terrorism tears people apart. The Russian Revolution in 1917 started because of the political oppression and ended in a dictatorship because humans are power hungry. It also continues to leave citizens with anxiety and stress and they can’t trust any leaders. Political oppression affects daily residents because we trust our will take care of us and when the leader is corrupt, people react with violence and terrorism. When these things happen in extreme measures, it becomes utter chaos. But political oppression can happen in the smallest ways. When I was in fifth grade. The teacher abused her power by locking me in a room for 45 minutes and my classmates were very angry at this injustice. To clarify this statement, I will explain furthermore. I was having conflict with another girl in my grade, let s call her Em. I had already went to my teacher and the principal of the school about the issue because she would make fun of me and spread rumors. Em told the guidance counselor her side of the story and when I was sent to resolve this issue, the counselor wouldn’t allow me to speak. In fact, she told me (I quote), â€Å"I don’t like your character†. Of course when you’re ten years old andShow MoreRelatedThe Russia n Revolution Of 19171109 Words   |  5 Pagessole cause of the Russian Revolution of 1917. Even before the outbreak of war, the Russian population were largely dissatisfied with the government under the Tsarist regime. Though the Great War played a role in sparking the Russian Revolution, with much of the unstable faith in the Tsar collapsing in Military Russia, it would be naà ¯ve to discredit the mounting economic and social pressures that contributed to the fall of the Tsarist Regime, and the beginning of the Revolution. Leading up to theRead MoreThe Russian Revolution Of 19171619 Words   |  7 PagesThe Russian Revolution of 1917 involved the collapse of an empire under Tsar Nicholas II and the rise of Marxian socialism under Lenin and his Bolsheviks. It sparked the beginning of a new era in Russia that had effects on countries around the world. In the years leading up to the Russian Revolution of 1917, the country had a succession of wars. These were, The Crimean War (1854-56), The Russo-Turkish War (1877-78), The Russo-Japanese War (1904-1905), and World War I (1914-18). All of these requiredRead MoreThe Russian Revolution Of 1917943 Words   |  4 PagesThe Russian Revolution of 1917 was an event that many historians have offered different perspectives on, as it was the start of a regime that greatly impacted the history of totalitarianism. Though much went on during 1917, the February Revolution and the fall of Tsarist regime was an event that created dialogue and prompted historians to pose perspectives as to what factors contributed to the Russian Monarchy ending in catastrophe. Many of these perspectives are focused on personalities. Some historiansRead MoreThe Russian Revolution Of 19171594 Words   |  7 PagesThe Russian Revolution of 1917 did not just suddenly happen overnight, just as there was no main reason w hy it happened. The Revolution was more like a virus or bad bacteria. At first you barely notice it, even though you know it is there, but soon it starts to multiply and take over your body and before you know it you have been diagnosed with a terminal illness. There are about 4 or 5 significant reasons why there was the revolution of 1917, with the Russian Tsar Nicolas II to be the blame forRead MoreThe Russian Revolution Of 19171646 Words   |  7 PagesThe Russian Revolution of 1917 brought with it the fall of 300 years of Romanov rule and marked the beginning of the transition of Tsarism to Communism, from which Lenin established the Union of Soviet Socialist Republics, succeeded by Stalin. The Revolution is worthy of investigation as it is arguably the most significant event of the 20th century, considering that it helped shape many other subsequent events such as the Second World War and the Cold War. The Bolsheviks’ triumph can be accountedRead MoreThe Russian Revolut ion Of 19171946 Words   |  8 Pages The Russian Revolution of 1917 set the country on a course that few other countries took in the 20th century. The shift from the direction of a democratic, parliamentary-style government to a one party communist rule was a drastic change that many did not and could not predict. Looking back on this key moment in Russian history, many historians ask the question ‘why did the political power in Russia shift to the Bolsheviks’? Since the revolution in 1905 Russia was becoming progressively more democraticRead MoreThe Russian Revolution Of 1917848 Words   |  4 PagesThe Russian Revolution of 1917 was a product of growing agitation within Russia as a result of various factors, both internally and externally of Russia. The detachment of the Tsar to the wants and needs of the people, in concurrence with their involvement in World War One, led to an uprising and revolution. Many historians describe the outcomes of this revolution using Marxist theory, explaining the key ideologies that come in to play as the revolution comes to an end and the newly established BolshevikRead MoreThe Russian Revolution Of 19171563 Words   |  7 PagesThe Russian Revolution of 1917 swept the country into an entirely new epoch, changing a monarch-led country into the Soviet Union and spreading the red of communism in waves through generations. A powerful team of Vladimir Lenin and Leon Trotsky organized the Bolsheviks, or Red Army, in political and military strategy against the Menshevik White Army. Part of their success came from the lack of unification of the Mensheviks. While the White Army banded together under a simply ‘anti-Bolshevik’ policyRead MoreThe Russian Revolutions of 1917 Essay1326 Words   |  6 PagesThe Russian Revolutions of 1917 There were two revolutions that occurred in Russia in 1917. The first one, in February, overthrew the Russian monarchy. The second one, in October, created the world’s first Communist state. The Russian revolutions of 1917 involved a series of uprisings by workers and peasants throughout the country and by soldiers, who were predominantly of peasant origin, in the Russian army. Many of the uprisings were organized and led byRead More1917 Russian Revolution Essay1114 Words   |  5 PagesRussian Revolution Essay. Throughout history there have been many revolutions between the population of a country and its government. People always want change, usually in the directions of freedom, peace and equality and in the lead up to the 1917 Russian revolution; there were a variety of social, political and economic situations that all played their part. In the years leading up to the revolution, Russia had been involved in a series of wars. The Crimean war, The Russo-Turkish war, The Russo-Japanese

Cell and Molecular Biology Free Essays

Cell and Molecular Biology Final Name: Hadeel Binomar30 pts. Protein misfolding can be an aspect of several different human disorders, including cystic fibrosis, Alzheimer’s disease, and atherosclerosis. Many times, the misfolded protein is a membrane protein. We will write a custom essay sample on Cell and Molecular Biology or any similar topic only for you Order Now In fact, a type of diabetes insipidus results from a mutation in the G-protein-coupled vasopressin 2 receptor that prevents the protein from making it to the cell membrane A) Describe how this type of receptor would normally get targeted to the membrane (from the beginning of translation) and B) then propose one mechanism by which the mutation could cause a lack of proper targeting. One of the most important protein’s target is G protein-coupled receptors, several signaling mechanisms depend on this type of receptor to change both internal and external stimuli to the intracellular responses. Basically, one of the G couple receptor subfamilies is G-coupled Vasopressin-2- Receptor (V2R), and this receptor is going through a strict quality control process at the endoplasmic reticulum, which presents the only correctly folded protein to gets through the secretory pathway. The primary function of the V2 receptor is to activate the attached G protein that bound to the ? subunit then phosphorylated to GTP. The G protein couple receptor then activates the enzyme adenylate cyclase that catalyzes the reaction in the ER and forms cAMP from ATP. After that, cAMP acts as a second messenger and activates a protein kinase that phosphorylates the integral membrane proteins on the cell surface. Moreover, the secretory pathway organelles’ and the plasma membrane both are first introduced into the Endoplasmic reticulum, and the co-translationally proteins that can cross the ER are synthesized by the ribosome first then binds by chaperones to gets moves to the ER surface using GTP that allows them to move toward the receptor then release it. The soluble proteins and the integral membrane proteins as I mentioned above, can be targeted through the ER and then translocated by the same mechanism.Further, several mutations occurring in the transmembrane region which affect the structure of the protein. These are multiple mutation sites, such as mutations occurring in the amino acid residues which was acting as a causative agent for human disease. Also, there are other mutations occurring on the single site position that will affect the translation mechanism and cause many human diseases like: cystic fibrosis, Alzheimer’s disease, and atherosclerosis that proves the function of V2R protein which plays important role in the translation during the protein folding process. One of the mechanism that may a reason for lacking the proper target protein is when the mutations of the CFTR gene occurring and affect the function of the chloride ion channels and cause defect in the protein sequences which lead to the production of diseases and misfolded of the proteins that are unable to recognize their functional destinations. Otherwise, Lack of the stop signals is another issue that prevents the protein from getting into the surface of the ER, also called the non-stop decay cellular pathway, because lack of this stop signals prevents mRNA from synthesis and translate the proteins, these consider as a point mutation that inhibits the essential stop codons. 30 pts. Describe the experiment shown in figure 3 from the paper we discussed in class (Miller et al, 2003). (A) In your description, consider the following questions: Why did they do it? How did they do it? What did they learn? (B) Diagram the results that you would expect to see in Lanes T, 1, 2, 3, and 4, if the amino acid signal DID in the protein Gap1p was mutated to random amino acids and tell why; and (C) Give two possible (different) results that might occur if the amino acid signal LxxLE in Bet1p was mutated to the amino acids DID (which are the signal in Gap1p). Diagram the results expected in Lanes T, 1, 2, 3, and 4 and explain why you predicted this result for each case.left20840701.A001.A4467225201739500The experiment was performed to study the role of cargo binding domain of Sec24p in the process of protein sorting. To perform this study, both mutant and wild types subunit Sec23/24p and Sec23/24L616W were harvested from microsomal membranes. The immunoblotting assay performed to quantify cargo molecules using radio-labeled secondary antibodies. Comparison of the mutant subunit with wild type illustrated omission of some molecules in mutant one, these molecules were cargo protein molecules. While some of them are packed in a way that similar to the wild-type. It meant that there were some signals that remained unaffected although mutation was there. Unexpectedly, it was found that in these unaffected molecules of mutation in Sec23/24p, packaging was better than the wild type. Further, they found the proteins that were highly affected had Bet1p and Gap1p/Sys1p chimera, because they completely depending on the Sys1p di-acidic of COPII vesicles. If the amino acid signal DID in the protein Gap1p was mutated to random amino acids, the resulting bands would be seen as in figure 1. A because the amino acids might be present in all the lanes. And Gap1p is required for di-acidic motifs to fuse together with the COPII vesicles at the mutated domain. Also, Sys1 peptide is not involved in Sec 23/24p hence its mutation is not contained in a di-acidic motif. If the signal LxxLE was mutated to the DID, the expected Bet1p packaging would be shown in figure 2. A as not be seen in lanes containing Bet1p because the amino acid signal LxxLE does not exit after mutating to amino acids DID. The second probability for the Bet1p would be expected to bind with the vesicle for packaging when it interacts with di-acidic motifs which is needed as shown in figure 2.B290512515621000581025113030004781550412752.B002.B6286501346202.A002.A20 pts. Explain the experiment shown in Figure 5C from the Shen et al. (2018) paper on the phosphorylation of CDC25 that we discussed in class. In addition, be sure to also address the following: A) why did they do this experiment (the central issue); B) what did they learn; and C) what is another control experiment they could have done? D) Would these results change if you added a constitutively active form of LKB1 to the reaction? If so, how and why? A) Overall, the main purpose of this paper is to explain how the division of cells is highly regulated such that cells that fail to pass some specific stage-based tests cannot advance to the proceeding stages. In this particular experiment, HeLa cells were subjected to chemicals that are known to activate the enzyme AMPK. Also, the main catabolic processes that are involved to generate energy for cells to transition from G1/G2 were determined by the application of radiochemical approaches, the experiment required to approve how highly conserved cellular energy sensor can significantly delay mitosis entry and activation of AMP-activated protein kinase (AMPK). Further, Wee 1 family inactivates the cell cycle G2/M Phase which is controlled by Cdc3/cyclic B (mitotic cyclin-dependent kinase complex). They found that AMPK-dependents phosphorylation of CDC25C arranges a metabolic control point for the M-phase transition and the cell cycle phase G2. B) Also, they learned that suppression of Wee 1 or acute induction partially reinstates mitosis ingress in the circumstance of activated protein kinase (AMPK). This experiment showed that when Phosphorylates Cdc25 is in a distributive and disordered state, it results into ultra-sensitivity in protein phosphorylation. C) For another control experiment, they might try exposing the U2OS (cell line) clones conditionally exhibiting Cdc25A etoposide. That will help to test whether Cdc25A degradation is significant for the G2 control point or not.D) If they add an active form of LKB1 to the reaction, the results will not change, because in cells LKBI activity inhibits AMPK activation in response to different stimulations. Also, LKBI is lost upon consistent isolation and therefore no effects of phosphates observed.20 pts. Briefly describe the role of cyclin-CDK in the cell cycle and give an example of positive and negative control in this system. Also, describe how cell cycle regulation links to the stimulation of apoptosis at the molecular level. In the beginning, the cell cycle depends on many basic factors that control the regulation process starting from the signal transcription molecules, growth factors and the Cyclin Dependent Kinases enzymes include the checkpoints which control the transition process between the cell cycle phases by binding to the cyclin proteins CDKs then phosphorylate other proteins to transfer from one phase to another. The role of transcription factors is to turn on the signals for gene expression, DNA replication, and cell divisions. As an example of CDKs, cyclin-dependent kinase 1 CDK1 is a cell division cycle protein homolog 2, that has a primary role in human cancer cells because CDK1 rather than any types of CDKs is fatal to the mutated version of MYC- dependent cancer that leads to a depletion of oncogenes like (Fos and Jun) in human cancer cells. Fos and Jun are combined forms of the transcription factor called AP1 that activates the delayed response genes such as cyclin D and CDK4. Recent studies reveal that the reason for the MYC breast cancer cells duplation is targeting CDF1 exhibit any other CDKs cell lines. Also, CDK1 inhibition can control and target the cancer cells in human and both phosphorylation and expression of MYC during the cell cycle process. To initiate intracellular signaling pathways and stimulate the cell cycle entry, mitogens substance bind to the cell surface receptor with the activation form of GTPase Ras that activates MAP kinase cascade. That will lead to the expression of encoding gene of the transcription regulatory protein like MYC. Moreover, E2F transcription factor is a target for cyclin D and CDKs that stimulate proteins expression to initiate S phase, also E2F regulated by the tumor suppressor gene Rb (Retinoblastoma protein). At early G1 Phase, Rb protein combined with E2f to form the histone deacetylases protein that remains chromatic condensed, then cyclin kinase phosphorylates Rb protein, causing it to disassociate from E2F. That allows recruitment of histone acetylates, which decondense the chromatin and helps transcription complexes to form in G1 and S phase and to form a positive feedback. For the negative control, if there are no growth factors present to stimulate the synthesis of Cyclin D in the new cell, Rb phosphorylated will turn off, and Rb will rebind to E2F, then the cell cycle will stop and that will lead to many negative results like prevent it to bind with DNA, or DNA damage and cells will return to the G0 phase. Apoptosis is a consequence of DNA damage; if the damage is not repaired, the cell cycle will divert towards apoptosis, otherwise, if the cell has DNA defects and fail to undergo apoptosis, that will change to the cancer cell. G1 phase regulators such as P53 and E2F are essential to promote the cell regulations and eliminate any damage or abnormal changes during the cell cycle. P53 has a primary function to prevent any mutation in DNA during cell progression, so any defect in P53 will lead to cancer, and it’s usually mutated in cancer cells. Further, Rb protein considers as a tumor suppressor and also promotes apoptosis. Additionally, most human cancers have inactive Rb protein, either mutated Rb or the non-phosphorylated (inactivated form) of Rb protein How to cite Cell and Molecular Biology, Papers

Article Review of Decision Support Systems-Samples for Students

Question: Write the article review on decision support systems. Answer: Article review of decision support systems Organizations in general use Decision Support Systems (DSS) to give PC based help to pioneers blamed for dealing with semi-sorted out and unstructured issues. Studies exhibit that DSS is fruitful if the customers' arrangement objectives or execution wants of the system are met. This is in light of the fact that the information needs of the customers (the pioneers) are appropriately met by the DSS (Chou Chang 2008) Furthermore, late data frameworks consider utilize subjective measures, for example, client encounter, saw happiness and convenience, to pressure the significance of psychological and full of feeling observations in DSS. Most associations began with information handling frameworks that help exchange preparing and develop administration data frameworks to help strategic and vital basic leadership. In a previous couple of years, another kind of frameworks called a Decision Support System (DSS) has picked up prevalence in the data framework field. The topic of estimating the effectiveness of DSS has all the earmarks of being the fortune of the client i.e. perceived effectiveness. (Ben-Zvi, 2010). Basing my arguments on the article, a gap on literature review is well elaborated. Several studies have been carried out by various scholars to determine the effectiveness of DSS in different settings. For instance, Bharati Chaudhury (2004), researched online choice emotionally supportive networks. Crowston et al. (1999) inspected open and bias-free source programming improvement settings. According to Reinig (2009), he considered community-oriented advancements, for example, gather emotionally supportive networks and their effect on execution. Those examinations primarily centered around the direct impacts of framework outline and use on results and client execution. Less DSS considers have incorporated choice process factors, such as saw helpfulness, fulfillment, satisfaction, and saw ease of utilization (Kamis Stohr 2008). The generally modest figure of concentrates that put in place choice process factors in studies for might be the aftereffect of the regularly utilized authori tative setting for such investigations, where process factors such as states of mind may seem not so much vital but rather blander and along these lines difficult to catch or measure. Likewise, when DSS fill the main need of achieving a specific objective, scientists' consideration is typically centered on that objective (and approaches to accomplish it) and less accentuation is set on DSS process factors.( Kamis et al., 2008). Additionally, experimental investigations that measure apparent effectiveness display contradicting outcomes. A few analysts report the effective execution of DSS (Garrity et al., 2008) According to Chan (2009), different researchers give no help to the preface that the utilization of DSS enhances individual or collective choice-making adequacy. In an investigation of undertaking multifaceted nature, Dulcic et al (2012), found that the DSS did not influence subjects' execution. Courtney et al (2008), contended that a large number of the choices they checked in their research facility DSS research were "ill-structured. According to the article, a simulation method was used to conduct the research. On that regard, DSS is felt through the simulation. The research is expanded by moving the concentration to the frameworks, the clients, and the effect on execution. Classes of understudies framed gatherings and took an interest in a reenactment work out. The gatherings, mimicking organizations in an industry, created DSS that were later described also, examined. Moreover, a few factors identified with DSS seen adequacy were assessed and contrasted with gathering execution. According to Ben-Zvi (2012) a simulation case with 652 senior graduate understudies who made DSS and expounded on the systems made. The article demonstrates that DSS clients who see the framework as compelling connect to enhanced organization execution. However, investing noteworthy HR in building up a framework does not really ensure improved execution. Moreover, the examination embodies how client characteristics can affect apparent effectiveness (Chen and Lin, 2009). The effectiveness of the simulation was measured by how the company performed. In terms of net profits, market share, investment and equity return. Net profit was influenced by the organization's choices, recreated client conduct, and the opposition alternate organizations in the business. Around the complete of each run, after the last course of action of decisions had been made, each social affair was required to show its DSS in class and to introduce a report which incorporated: an importance of the degree of the structure, a decision examination, a system design and a discussion of the dedication of the structure in achieving the get-together's objectives in the midst of the entertainment. At that same assembling, each one of the understudies was requested to complete a short individual poll on the DSS undertaking (Mahdavi et al., 2010). The findings show that most of the groups selected information officer during the different runs. All associations point by point developing an information system, but none of the associations uncovered genuine changes in the midst of the run. About 65% of the companies developed a complicated tool of analysis where-else the 35% developed a graphics output (shown in the article) the refinement. Furthermore, multifaceted nature of the models used varied on a very basic level from essential spreadsheet examinations to an intricate straight model. It can't be attested that the scattering of characteristics of structures accurately measures that as a general rule, the level of an average assortment of systems made in view of existing instruments, appears to be very genuine. To ensure that the results were valid, they were compared to the previous findings. A few factors identified with DSS saw viability was broke down. Next, organization execution was critically analyzed with respect to the created DSS. At that point, took a look at framework multifaceted nature and inner consistency among the questionnaire's things. The article denotes several implications for management practice in a company. The results demonstrate a solid and huge reliance of organization performance on five factors: framework's handiness, client fulfillment, the commitment of the DSS to the assorted utilitarian regions and to the whole organization achievement and whether the DSS lived up to its desires. It appears that the more prominent the fulfillment from the created framework in meeting its planned point as set by the clients, the better the organization's execution in the reenactment. Utilizing the framework additionally adds to organization execution; in any case, this outcome isn't measurably critical. System complexity was also put in place to determine the perceived effectiveness, company execution, and user satisfaction. The level of complexity was analyzed according to the previous studies and then developed systems from all runs. Diverse levels of many-sided quality were resolved: plain many-sided quality, direct and multifaceted many-sided quality. Unmistakably organizations with plain multifaceted nature communicated most lessened levels of clear viability and customer satisfaction and moreover displayed an underneath ordinary execution. Organizations with a moderate framework many-sided quality communicated the most abnormal amounts of apparent effectiveness whats more, client fulfillment and furthermore exhibited the most noteworthy execution, in spite of the fact that moderately near that of organizations with a multifaceted system framework. The article suggests that the reasonability of reenactments as stages for completing DSS is two ways. In the first place, members hone the claim to fame of essential initiative; individuals are stimulated, induced, what's more, attempt to settle on better decisions; they end up being adequately drawn in with the reenacted fundamental authority process and in their favored progression of MIS and DSS. Second, because the reenactment is especially practical, the individuals themselves plot the association between the essential administration shapes, the created information systems (Lin Tu, 2012) Moreover, the outcomes have implications for practitioners and researchers. For researchers, the investigation illustrates the significance of including subjective measures while inspecting DSS adequacy. All things considered, researchers should be careful about utilizing distinctive measures of framework adequacy and execution. While a few measures are emphatically connected with framework saw viability or organization execution, different variables don't present a coordinate effect. Furthermore, analysts ought to plainly determine what the correct nature of the deliberate factors Practitioner implications are also very significant. The article clearly shows the essential connection amongst complexity and execution to demonstrate that multifaceted frameworks don't really ensure better outcomes. In general, simulation urges understudies to apply logical ideas learned through formal lessons to make a framework that backings critical thinking exercises utilizing the accessible information. A definitive outcome will be more viable MIS and DSS in reality. Additionally, practitioners need to comprehend that a non-appearance of strong behavioral indications of framework acknowledgment, foster in describing a framework or usage of the framework may not so much achieve a negative outcome. User contribution in a framework improvement or then again configuration process may connote a superior specialized or operational fit. For instance, a superior utilization of technology yet as this investigation appeared, this does not really recommend upgraded performance. Truth be told, there could be extremely different variables that affect execution. By understanding the obvious measures of DSS reasonability and association execution, specialists could make an interpretation of data identifying with those measures more correctly. Despite the findings in the article, credibility issues of the article are noted. The simulation is exceptionally mind-boggling and wide to give issues and practical basic leadership reproduction. No particular reenactment that can incorporate all progression of data frameworks. Since the reenactment decisions are more shortsighted than those of this present reality, the DSS required helping the decisions are less solid than those in actuality (Sharma et al., 2010). Thus, the appropriateness and all-inclusive statement of the discoveries ought to be joined by another examination and basically dissected. There is have to know the way recreations can be coordinated to investigate the more unpredictable flow of DSS. It is likewise not certain whether the self-reports reflect genuine lead of framework customers in actuality. Future examinations can give definite outcomes utilizing target measures. References Ben-Zvi, T., 2010 The efficacy of business simulation games in creating Decision Support Systems: An experimental investigation.Decision Support Systems,49(1), pp.61-69. Ben-Zvi, T., 2012 Measuring the perceived effectiveness of decision support systems and their impact on performance.Decision Support Systems,54(1), pp.248-256. Bharati, P. and Chaudhury, A., 2004 An empirical investigation of decision-making satisfaction in web-based decision support systems.Decision support systems,37(2), pp.187-197. Chan, S.H., 2009 The roles of user motivation to perform a task and decision support system (DSS) effectiveness and efficiency in DSS use.Computers in Human Behavior,25(1), pp.217-228. Chen, L. and Lin, C., 2009 DSS interaction: a simulation experiment.SIGHCI 2009 Proceedings, p.17. Chou, S.Y. and Chang, Y.H., 2008 A decision support system for supplier selection based on a strategy-aligned fuzzy SMART approach.Expert systems with applications,34(4), pp.2241-2253. Courtney, J., Merali, Y., Paradice, D. and Wynn, E., 2008 On the study of complexity in information systems.International Journal of Information Technologies and the Systems Approach,1(2). Dulcic, Z., Pavlic, D. and Silic, I., 2012 Evaluating the intended use of Decision Support System (DSS) by applying Technology Acceptance Model (TAM) in business organizations in Croatia.Procedia-Social and Behavioral Sciences,58, pp.1565-1575. Field, D., Garrity, G., Gray, T., Morrison, N., Selengut, J., Sterk, P., Tatusova, T., Thomson, N., Allen, M.J., Angiuoli, S.V. and Ashburner, M., 2008 The minimum information about a genome sequence (MIGS) specification.Nature biotechnology,26(5), p.541. Kamis, A., Koufaris, M. and Stern, T., 2008 Using an attribute-based decision support system for user-customized products online: an experimental investigation.MIs Quarterly, pp.159-177. Lin, Y.L. and Tu, Y.Z., 2012 The values of college students in business simulation game: A means-end chain approach.Computers Education,58(4), pp.1160-1170. Mahdavi, I., Shirazi, B. and Solimanpur, M., 2010 Development of a simulation-based decision support system for controlling stochastic flexible job shop manufacturing systems.Simulation Modelling Practice and Theory,18(6), pp.768-786. Malone, T.W., Crowston, K., Lee, J., Pentland, B., Dellarocas, C., Wyner, G., Quimby, J., Osborn, C.S., Bernstein, A., Herman, G. and Klein, M., 1999 Tools for inventing organizations: Toward a handbook of organizational processes.Management Science,45(3), pp.425-443. Nunamaker Jr, J.F., Reinig, B.A. and Briggs, R.O., 2009 Principles for effective virtual teamwork.Communications of the ACM,52(4), pp.113-117. Sharma, R., Reynolds, P., Scheepers, R., Seddon, P.B. and Shanks, G.G., 2010 August. Business Analytics and Competitive Advantage: A Review and a Research Agenda. InDSS(pp. 187-198).